A Bioinspired Platform Technology
State of the art research among material scientists, chemists, microbiologists, and biomedical engineers at the University of California, Los Angeles has led a customizable solution enabling the broad-based use of zwitterionic chemistry on implanted medical devices and beyond
Read more about our technology in
our Advanced Materials publication
Unleashing the Power of Zwitterions
Zwitterion chemistry has long been recognized as one of the most powerful antibiofouling technologies providing resistance to bacterial infections, inflammation, and blood coagulation.
Emulating the chemistry of the phospholipid bilayer that encompasses every cell in the body, zwitterionic polymers bind to water electrostatically to create an extremely thin surface hydration layer, preventing attachment of organic materials.
Resisting microbial colonization
Our patented treatment creates a covalent bond with it’s substrate, resulting in a permanently transformed medical device surface capable of repelling bacteria and restricting the growth that promotes infection.
*Data on file available by request
Protecting against thrombosis.
Catheter related thrombosis is a pervasive concern among patients receiving dialysis, cancer treatments, and many other supportive care therapies that use central venous catheters & PICC lines.
The Silq treatment offers the potential for a new generation of medical devices that could reduce the frequency of these complications and improve patients’ quality of life.
As published in Advanced Materials, in accordance with ISO 10993: Biological Evaluation of Medical Devices, Part 4: Selection of Tests for Interactions with Blood (2017) guidelines, it was found that Silq treated silicone tubes had a 50% reduction in surface thrombus coverage (p<0.05). This calculation does not account for the significantly larger 3-dimensional size of the blood clots seen on the untreated silicone tubes.
*Data on file available by request
